About Me
Welcome to my research webpage! I am an Assistant Professor (Research Track) at the University of Utah, specializing in bioinformatics and computational oncology. My research bridges computational approaches with translational oncology, contributing to clinically meaningful discoveries.
I received my Ph.D. in Medicine (Computational Biology focused) from the University of Manchester in 2022, and my BSc (First Class) in Biomedical Science from the University of Queensland in 2011.
My current research interests include:
- Pan-cancer scRNA-seq analysis for drug discovery
- Immune-related adverse events and immunotherapy efficacy
- Plasma cfDNA genomics for prostate cancer prognosis
- Clinical trial data mining and pattern recognition
Research Projects
Pan-Cancer scRNA-seq Drug Discovery
Focus: Immunotherapy toxicity and efficacy
Analyzing pan-cancer single-cell RNA sequencing data to discover targetable drug candidates that mitigate immune-related adverse events while preserving immunotherapy efficacy. This work aims to improve patient outcomes by reducing toxicity without compromising treatment effectiveness.
Prostate Cancer Genomics
Focus: Plasma cfDNA and clinical outcomes
Utilizing plasma cell-free DNA whole genome sequencing to develop and implement multi-gene risk score algorithms for predicting clinical outcomes in prostate cancer patients. This research contributes to personalized medicine approaches in oncology.
Clinical Trial Data Mining
Focus: Immunotherapy toxicity patterns
Analysis of over 400,000 clinical trials to identify patterns of immunotherapy toxicity. This large-scale data analysis helps understand adverse event profiles and improve patient safety in cancer treatment.
Selected Publications
Investigation of high-dose ipilimumab combination therapy effectiveness in advanced melanoma patients who progressed on standard treatments.
Development of a multi-gene risk scoring algorithm using plasma cfDNA whole genome sequencing for predicting clinical outcomes in prostate cancer.
Comprehensive analysis of over 400,000 clinical trials to identify patterns and predictors of immunotherapy-related adverse events.
For a complete list of 35+ publications, see my Google Scholar profile.
Curriculum Vitae
You can download my complete CV here: CV PDF
Education
- Ph.D. in Medicine (Computational Biology focused), University of Manchester, 2022
- BSc (First Class), Biomedical Science, University of Queensland, 2011
Professional Experience
- Assistant Professor (Research Track), University of Utah, 2024-current
- Postdoctoral Fellow (Translational Bioinformatics), University of Utah, 2022-2023
- Bioinformatics Analyst, Cancer Research UK Manchester Institute, 2015-2016
- Bioinformatics Research Assistant, Cancer Research Malaysia, 2012-2014
Awards & Honors
- Young Scientist Award, Mid-South Computational Biology & Bioinformatics Society, 2023
- Ph.D. scholarship, Cancer Research UK Manchester Institute, 2016-2022
- Travel Conference Award, European Conference On Computational Biology, 2021